Ascorbic acid plays an important role in regulating the redox processes, carbohydrate metabolism, blood coagulation, tissue regeneration, increases halotestin tablets resistance of the organism. Ascorbic acid (vitamin C) is not formed in the human body, and comes only with food. With a balanced and nutritious food a person not deficient in vitamin C .Prevention and treatment of hypovitaminosis of vitamin C. With increased the body’s need for vitamin C: in the period of active growth in children, pregnancy, breast-feeding, with halotestin tablets increased physical and mental stress, fatigue, stress conditions, during the recovery period after a long and serious illness: Hypersensitivity to the drug. Do not assign large doses to patients with increased blood clotting, thrombophlebitis and a tendency to thrombosis, as well as in diabetes mellitus and conditions associated with increased blood sugar.
Dosing and Administration
- The drug is taken orally, after meals. From prevention to prescribe: Vzroslym- 50-100 mg / day .; children 25 mg / day. During pregnancy and lactation 300 mg / day. . for 10-15 days, followed by 100 mg / dayWith the purpose of treatment is prescribed: Vzroslym- 50-100 mg 3-5 times a day; children 50-100 mg 2-3 times a day. The duration of treatment depends on the nature and course of the disease and the doctor recommended.
Allergic reactions to the drug, irritation of the gastrointestinal tract (nausea, vomiting, diarrhea, stomach cramps), when used in high doses – giperoksalaturiya and the formation of urinary stones halotestin tablets of calcium oxalate; depression insular pancreatic apparatus function (hyperglycemia, glucosuria). Laboratory findings: thrombocytosis, giperprotrombinemiya, erythropenia, leukocytosis, hypokalemia.
Use during pregnancy and breastfeeding
minimum daily need in ascorbic acid in II-III trimesters of pregnancy – about 60 mg. The minimum daily requirement for lactation – 80 mg. Mother’s diet containing adequate amounts of ascorbic acid is sufficient for the prevention of vitamin C deficiency in an infant (it is recommended not to exceed a maximum monthly nursing mother needs ascorbic acid).
term use of high doses (above 1 g) – headache, increased excitability of the central nervous system, insomnia, nausea, vomiting, hyperacid gastritis, ulceration of the mucosa of the gastrointestinal tract, heartburn, diarrhea, difficulty urinating, staining urine red color, hemolysis (in patients with a deficiency of glucose-6-phosphate dehydrogenase), inhibition of the function of insular pancreatic apparatus (hyperglycemia, glucosuria), hyperoxaluria, nephrolithiasis (from calcium oxalate), damage to the glomerular apparatus of the kidneys, moderate pollakiuria (when receiving doses of 600 mg / day).
The decrease in capillary permeability (possible deterioration of the trophic tissue, increased blood pressure, hypercoagulation, the development of microvascular complications).
Interaction with other drugs
increases the blood concentration of penicillin and tetracyclines; at a dose of 1 g / day of ethinyl estradiol increases bioavailability. Improves the intestinal absorption of iron (ferric iron translates into ferrous);may increase the excretion of iron while the use of deferoxamine. Acetylsalicylic acid (ASA), oral contraceptives, fresh halotestin tablets juices and alkaline water reduces the absorption and assimilation. In an application with ASA increased urinary excretion of ascorbic acid and reduced excretion of ASA. ASA reduces absorption of ascorbic acid is about 30%. It increases the risk of crystalluria in the treatment of salicylates and sulfonamides short-acting, slow excretion by the kidneys of acids, increases the excretion of drugs that have an alkaline reaction (including alkaloids), lowers blood levels of oral contraceptives. Increases total clearance ethanol which, in turn, reduces the concentration of ascorbic acid in the body. Preparations quinoline series (and other fluoroquinolones.), Calcium chloride, salicylates, steroids with prolonged use deplete ascorbic acid. In an application reduces the chronotropic effect of isoprenaline. With prolonged use or application in high doses may interfere with the interaction of disulfiram-ethanol. In high doses, it increases the renal excretion of mexiletine. Barbiturates and primidone increase the excretion of ascorbic acid in the urine. It reduces the therapeutic effects of antipsychotic drugs (phenothiazine derivatives), tubular reabsorption of amphetamine and tricyclic antidepressants.
In connection with the stimulating effect of ascorbic acid on the synthesis of glucocorticoid hormones, it is necessary to monitor adrenal function and blood pressure. With prolonged use of high doses of possible inhibition of the function of insular apparatus of the pancreas, so the treatment needs to be monitored regularly. In patients with a high content of iron in the body, ascorbic acid should be used in minimal doses. Appointment of ascorbic acid in patients with rapidly proliferating and rapidly metastasizing tumors may increase during the process. Ascorbic acid is a reducing agent, can distort the results of various laboratory tests (blood glucose, bilirubin, transaminases, LDH).
Tablets 25 mg; Tablets 25 mg (orange, cherry, pear, lemon, mint, black currant):
10 tablets in parchment or waxed paper, followed by wrapping in label cellophane paper or waxed.
On 12 tablets in blisters made of PVC film, aluminum foil printing lacquered or paper laminated or plastic laminated film.
in 2 blisters with instruction on use pomeschayyut in a pile of cardboard.
in 2 or 4 tablets in contour bezgyachakova packing paper laminate, or resin laminated film.
on 5 contour bezgyachakova packs of 4 tablets or 10 halotestin tablets contour bezgyachakova packs of 2 tablets, along with instructions for use are placed in a pile of cardboard boxed.
Before packing in a cardboard box, packaging cellophane or paper waxed packed in plastic bags of 50 packages.
in 100 – 500 packages of cellophane or waxed paper with an equal number of instructions for medical use, or packets with strip cellular or bezgyachakova packaging, placed in a cardboard box.
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